Renal involvement in chronic pulmonary tuberculosis

Area of Science:

• Nephrology
• Pulmonology
• Infectious Diseases

Background:

• Chronic pulmonary tuberculosis (TB) can affect multiple organs.
• Renal involvement in TB patients is not fully understood.
• Early detection of kidney issues is crucial for patient outcomes.

Purpose of the Study:

• To assess the spectrum of renal pathology in indoor patients with chronic pulmonary tuberculosis.
• To correlate clinical symptoms with biopsy findings.
• To understand the frequency of different kidney diseases in this population.

Main Methods:

• Study included 50 indoor patients diagnosed with chronic pulmonary tuberculosis.
• Patients were evaluated for urinary symptoms.
• Renal biopsy was performed on 35 patients for histopathological analysis.

Main Results:

• Common symptoms included frequent urination and dysuria.
• Urine cultures were positive for mycobacteria in 6% of patients.
• Renal biopsies showed interstitial nephritis (28.5%), amyloidosis (17.1%), glomerulonephritis (17.1%), and tubercular pyelonephritis (5.6%).

Conclusions:

• Chronic pulmonary tuberculosis is associated with diverse renal pathologies.
• Kidney biopsy is essential for diagnosing renal involvement in TB patients.
• Interstitial nephritis and amyloidosis are common findings in TB-related kidney disease.