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Related Concept Videos

Synteny and Evolution02:31

Synteny and Evolution

3.9K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
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Inclusive Fitness00:57

Inclusive Fitness

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Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help.
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Types of Selection01:46

Types of Selection

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Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
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Dihybrid Crosses01:18

Dihybrid Crosses

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Overview
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Frequency-dependent Selection01:21

Frequency-dependent Selection

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When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
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Limits to Natural Selection01:38

Limits to Natural Selection

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Organisms that are well-adapted to their environment are more likely to survive and reproduce. However, natural selection does not lead to perfectly adapted organisms. Several factors constrain natural selection.
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Comparing fine-scale mutation and recombination landscapes in rhesus macaque ( <i>Macaca mulatta</i> ) populations of Chinese and Indian descent inferred from both short- and long-read sequencing data.

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Inferring the demographic history of Chinese and Indian rhesus macaque ( <i>Macaca mulatta</i> ) populations from PacBio HiFi long-read sequencing data.

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Evolutionary genomics based on PacBio HiFi long-read sequencing data reveals the importance of structural variants in shaping population-specific differences between Chinese and Indian rhesus macaques ( <i>Macaca mulatta</i> ).

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Related Experiment Video

Updated: Mar 14, 2026

Assessment of Social Cognition in Non-human Primates Using a Network of Computerized Automated Learning Device ALDM Test Systems
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The Impact of Linked Selection in Chimpanzees: A Comparative Study.

Susanne P Pfeifer1,2,3, Jeffrey D Jensen4,2,3

  • 1School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland susanne.pfeifer@epfl.ch.

Genome Biology and Evolution
|September 29, 2016
PubMed
Summary
This summary is machine-generated.

Recombination rate is the main driver of nucleotide diversity in Western chimpanzees, showing a strong positive correlation. Other factors like telomeric distance and GC-content also influence variation.

Keywords:
chimpanzeenucleotide diversityselection

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Area of Science:

  • Genomics
  • Population Genetics
  • Evolutionary Biology

Background:

  • Nucleotide diversity varies across genomes due to mutation rates and selection.
  • A positive correlation between nucleotide diversity and recombination is commonly observed but difficult to interpret in some species.
  • Understanding these patterns is crucial for evolutionary studies.

Discussion:

  • Recombination rate is the primary predictor of nucleotide variation in Western chimpanzees.
  • Telomeric distance, GC-content, and CpG-island content are negatively correlated with nucleotide diversity.
  • These findings are compared to human patterns, considering effective population sizes and demographic histories.

Key Insights:

  • Recombination rate strongly predicts nucleotide diversity in chimpanzees.
  • Genomic features like telomeric proximity and GC-content significantly impact variation.
  • Comparative analysis with humans reveals species-specific evolutionary dynamics.

Outlook:

  • Further research can elucidate the precise mechanisms linking these genomic features to nucleotide diversity.
  • Comparative genomics studies can refine our understanding of evolutionary forces across primates.
  • Investigating demographic histories enhances insights into species-specific genetic variation patterns.