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Changes in intraventricular septal thickness, left ventrical wall thickness and left ventricular volume in obese
E H Archibald1, V A Stallings, P B Pencharz
1Hospital for Sick Children, Department of Pediatrics, University of Toronto, Ontario, Canada.
Abstract:
Ten obese adolescents (153 percent ideal body weight) underwent significant weight reduction over a two to three month period using a low calorie, low carbohydrate, protein diet. The subjects lost a mean of 13.9 +/- 4.3 kg, representing a decrease of 15.5 +/- 5.0 percent of initial body weight. Serial measures of intraventricular septal thickness (ST), left ventricular wall thickness (LVWT) and left ventricular volume (LVV) were determined by standard m-mode echocardiographic methods over 14 weeks to determine the effect of weight reduction on these indicators of cardiac size. The ST changed over the study period from 8.2 +/- 1.9 mm to 7.3 +/- 2.0 mm; the LVWT from 7.6 +/- 1.8 mm to 6.3 +/- 1.1 mm; and the LVV from 47.1 +/- 4.0 mm to 42.0 +/- 2.8 mm. These numerical decreases were not significantly different. Over this study period, the diet allowed weight loss with no apparent effect on the cardiac size (ST, LVWT, LVV) as measured by echocardiography in these obese adolescents.