Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Determination01:51

Determination

21.3K
During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In...
21.3K
Gastrulation01:56

Gastrulation

68.4K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
68.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of laryngeal tube evo with tracheal intubation during intra-arrest-ventilation using biphasic positive pressure ventilation - a prospective randomized controlled body donor study.

Critical care (London, England)·2026
Same author

Loss of Atoh8 Impairs Macroautophagy.

Cells·2025
Same author

Influence of different airway devices on intra-arrest ventilation during bag-valve-device ventilation - a prospective randomized controlled cadaver study.

Critical care (London, England)·2025
Same author

Proteomics of Duchenne Muscular Dystrophy Patient iPSC-Derived Skeletal Muscle Cells Reveal Differential Expression of Cytoskeletal and Extracellular Matrix Proteins.

Cells·2025
Same author

Neurodevelopmental Impact of Prenatal Stress: A Proteomic Analysis of Myelination Disruptions in the Avian Embryo.

Developmental neurobiology·2025
Same author

The Development of the Human Female Reproductive Tract. Part 1: Uterine Tube and Uterus.

Clinical anatomy (New York, N.Y.)·2025

Related Experiment Video

Updated: Mar 14, 2026

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression
11:48

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression

Published on: January 17, 2016

9.4K

Expression Pattern of Axin2 During Chicken Development.

Gesa Eckei1, Marion Böing1, Beate Brand-Saberi1

  • 1Department of Anatomy and Molecular Embryology, Ruhr-University of Bochum, Bochum, Germany.

Plos One
|September 30, 2016
PubMed
Summary

Axin2, a key regulator of Wnt signaling, shows dynamic expression during chicken embryo development. This study details Axin2 mRNA patterns in early embryogenesis, aiding understanding of Wnt pathway regulation.

More Related Videos

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
06:49

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay

Published on: January 12, 2022

3.7K
Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

Published on: February 2, 2016

8.5K

Related Experiment Videos

Last Updated: Mar 14, 2026

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression
11:48

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression

Published on: January 17, 2016

9.4K
Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
06:49

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay

Published on: January 12, 2022

3.7K
Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

Published on: February 2, 2016

8.5K

Area of Science:

  • Developmental Biology
  • Molecular Biology
  • Genetics

Background:

  • Canonical Wnt signaling is crucial for embryonic development in vertebrates and invertebrates.
  • Axin2 acts as a negative feedback regulator within the canonical Wnt pathway.
  • Understanding Axin2's role is vital for proper embryonic development.

Purpose of the Study:

  • To provide a detailed spatiotemporal analysis of Axin2 expression during chicken embryogenesis.
  • To investigate the dynamic expression patterns of Axin2 mRNA in various embryonic tissues.

Main Methods:

  • In situ hybridization was performed on chicken embryos.
  • Embryos were analyzed across developmental stages HH 04+ to HH 32.

Main Results:

  • Axin2 exhibits temporally and spatially restricted dynamic expression throughout chicken embryo development.
  • Specific expression data was obtained for Axin2 mRNA in early embryogenesis, somites, neural tube, limbs, kidney, and eyes.

Conclusions:

  • Axin2 expression is tightly regulated during chicken embryogenesis.
  • The findings contribute to a deeper understanding of Wnt pathway regulation in embryonic development.