Related Experiment Video
Updated: Mar 14, 2026
Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
SILVER NANOPARTICLES-DISK DIFFUSION TEST AGAINST Escherichia coli ISOLATES
Francisco Afrânio Cunha1,2, Kamila Rocha Maia2, Eduardo José Jucá Mallman1
1Universidade Federal do Ceará-UFC, Departamento de Química Analítica e Físico-Química Grupo de Química de Materiais Avançados(GQMAT). Campus do Pici, CP 12100, 60451-970 Fortaleza, CE, Brazil. E-mails: afraniocunha7@gmail.com; maome@superig.com.br; aubersonfarmaufc@gmail.com; pbafechine@gmail.com.
Abstract:
Nanotechnology can be a valuable ally in the treatment of infections. Silver nanoparticles (AgNPs) are structures that have antimicrobial activity. The aim of this study was to produce AgNPs by green methods, characterize these structures, and assess their antimicrobial activity against Escherichia coli associated with the antibiotic ciprofloxacin. AgNPs were characterized by spectroscopic and microscopic techniques. Antimicrobial activity was evaluated by the disk diffusion method against 10 strains of E. coli. The synthesized AgNPs showed a spherical shape and a size of 85.07 ± 12.86 nm (mean ± SD). AgNPs increased the activity of ciprofloxacin by 40% and may represent a new therapeutic option for the treatment of bacterial infections.
