Fluorometric Determination of Epinephrine: A Green Approach

Herein, a simple, sensitive and selective turn-on fluorescent method for the determination of epinephrine (EP), an important hormone and neurotransmitter, is described. The method is based on the interaction of EP with PEG6000 coated carbon nanoparticles (PCN) resulting in the fluorescence enhancement of PCN. A linear relationship was obtained between the fluorescence intensity and concentration of EP in the 9.90 × 10(-9) - 1.07 × 10(-7) M range; the detection limit being 7.59 × 10(-10) M. Furthermore, we demonstrated the application of the present approach in a synthetic urine sample, which suggested its great potential for diagnostic purposes.