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Updated: Mar 14, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Glomerular filtration rate in patients with psoriasis treated with etanercept
Paolo Gisondi1, Giampiero Girolomoni2
1Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy paolo.gisondi@univr.it.
Objective:
To estimate the prevalence of chronic kidney disease (CKD) and evaluate renal function in patients with moderate-to-severe chronic plaque psoriasis treated with etanercept (an anti-tumour necrosis factor-α drug).
Methods:
This retrospective cohort study included patients with moderate-to-severe chronic plaque psoriasis. Kidney function was evaluated using estimated glomerular filtration rate (EGFR).
Results:
The prevalence of CKD at baseline was 3.9% (two of 51 patients). EGFR was unaffected by etanercept therapy (83.6 ± 23.9 at baseline vs 82.2 ± 21.6 ml/min per 1.73 m2 after 6 months).
Conclusion:
EGFR was unaffected by 6 months' etanercept treatment. Physicians should be aware of the risk of CKD when providing comprehensive care to patients with moderate-to-severe psoriasis.
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