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Harmonization Initiatives in Europe.

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Harmonizing laboratory testing across Europe is crucial for modern medicine. The European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) is surveying and promoting initiatives for pre- and post-analytical harmonization to improve clinical laboratory data consistency.

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harmonizationtotal testing process

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Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Healthcare Harmonization

Background:

  • Clinical laboratory data are integral to medical protocols and guidelines.
  • Harmonization efforts must encompass pre-analytical, analytical, and post-analytical phases for comprehensive results.
  • Increasing reliance on standardized data necessitates broader harmonization initiatives.

Purpose of the Study:

  • To survey and summarize European harmonization initiatives in laboratory medicine.
  • To promote and disseminate effective harmonization strategies among European societies.
  • To initiate harmonization of nomenclature, units, and reference intervals at a European level.

Main Methods:

  • Establishment of the European Federation of Clinical Chemistry and Laboratory Medicine's Working Group on harmonization of the total testing process (WG-H).
  • Distribution of a questionnaire to European laboratory medicine societies to assess harmonization activities, particularly in pre- and post-analytical phases.
  • Collaboration with manufacturers for standardization efforts, such as color coding of blood collection tube closures.

Main Results:

  • A survey was conducted to understand the current status of harmonization activities across European laboratory medicine societies.
  • Identified promising harmonization initiatives for dissemination, focusing on pre- and post-analytical phases.
  • Initiated efforts to standardize nomenclature, units, and reference intervals.

Conclusions:

  • Future activities will promote best practices in blood sampling, storage, and transportation.
  • Initiatives will be undertaken to promote the use of SI units across all European countries.
  • A Task and Finish Group is actively working on standardizing the color coding for blood collection tube closures.