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Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time
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Primary Ovarian Malignant PEComa: A Case Report.

Joseph D Westaby1, Nesreen Magdy, Cyril Fisher

  • 1Department of Histopathology (J.D.W., N.M., M.E.-B.), Imperial College London Department of Pathology (C.F.), Sarcoma Unit, The Royal Marsden Hospital, London, UK Department of Pathology, (N.M.), National Cancer Institute, Cairo Department of Pathology (M.E.-B.), Alexandria Faculty of Medicine, Alexandria, Egypt.

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
|September 30, 2016
PubMed
Summary
This summary is machine-generated.

A rare ovarian tumor, perivascular epithelioid cell tumor (PEComa), was identified. This is the first reported case of a primary malignant PEComa originating in the ovary.

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Area of Science:

  • Oncology
  • Pathology
  • Gynecologic Oncology

Background:

  • Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms.
  • These tumors exhibit co-expression of melanocytic and smooth muscle markers.
  • PEComas are infrequently found in the female genital tract.

Observation:

  • A case of a malignant primary PEComa of the ovary is presented.
  • This tumor originated directly from the ovarian tissue.

Findings:

  • The study details the characteristics of this ovarian PEComa.
  • Differential diagnosis considerations for ovarian neoplasms are discussed.

Implications:

  • This case expands the known spectrum of PEComa presentation.
  • It highlights the importance of considering PEComa in the differential diagnosis of ovarian tumors.
  • Further research into ovarian PEComas may improve diagnostic accuracy and patient outcomes.