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Mild Hypothermia in a Child with Low-Dose Risperidone.

Katharina Grau1,2, Paul L Plener3, Maximilian Gahr1

  • 11 Dept. of Psychiatry and Psychotherapy III, University of Ulm, Germany.

Zeitschrift Fur Kinder- Und Jugendpsychiatrie Und Psychotherapie
|September 30, 2016
PubMed
Summary

Risperidone, an antipsychotic, can cause low body temperature (hypothermia). This case study highlights hypothermia in a child on low-dose risperidone monotherapy, even without other medications.

Keywords:
antipsychoticsconduct disorderhypothermiarisperidoneside effect

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Area of Science:

  • Pharmacology
  • Pediatric Psychiatry

Background:

  • Risperidone is a second-generation antipsychotic used for schizophrenia and aggression in pediatric patients.
  • Altered body temperature, including hyperthermia and hypothermia, is a known risk associated with risperidone.
  • Hypothermia has been anecdotally reported, often with concomitant medications.

Observation:

  • A case of hypothermia in a child treated with risperidone is presented.
  • The child was on a low-dose risperidone monotherapy.
  • No other medications were administered concurrently.

Findings:

  • Low-dose risperidone monotherapy was associated with hypothermia in a pediatric patient.
  • This finding contrasts with anecdotal reports where hypothermia typically involves comedication.

Implications:

  • Clinicians should be vigilant for hypothermia in children treated with risperidone, even at low doses and without comedication.
  • Further research is warranted to understand the mechanisms and prevalence of risperidone-induced hypothermia in pediatric populations.
  • This case underscores the importance of monitoring core body temperature in pediatric patients receiving antipsychotic treatment.