Related Experiment Video
Updated: Mar 14, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
15.2K
Group B Streptoccocal Meningitis and Ventriculo-peritoneal Shunts
M Crealey1, T Mandiwanza1, D Crimmins1
1Childrens University Hospital, Temple St, Dublin 1.
Irish Medical Journal
|September 30, 2016
Summary
Ventriculo-peritoneal (VP) shunt insertion is needed for 10% of infants with group B streptococcus (GBS) meningitis, often presenting with seizures and lethargy. This study provides the first Irish data on VP shunt rates in GBS meningitis.
Area of Science:
- Neonatal Neurology
- Pediatric Infectious Diseases
- Neurosurgery
Background:
- Group B Streptococcus (GBS) meningitis is a significant cause of infant morbidity.
- Hydrocephalus is a known complication of bacterial meningitis in infants.
- Data on the incidence of Ventriculo-peritoneal (VP) shunt insertion for GBS meningitis in Ireland is lacking.
Purpose of the Study:
- To determine the rate of VP shunt insertion in infants diagnosed with GBS meningitis in Ireland.
- To identify clinical predictors for VP shunt requirement in this population.
Main Methods:
- Retrospective case series.
- Analysis of 40 infants with GBS meningitis over a 6-year period.
- Review of clinical presentation and outcomes, including need for VP shunt insertion.
Main Results:
- Four out of 40 (10%) infants required VP shunt insertion for hydrocephalus.
- Infants needing VP shunts presented with seizures, lethargy, and low serum white cell count.
- This is the first study to report VP shunt insertion rates for GBS meningitis in Ireland.
Conclusions:
- Approximately 10% of infants with GBS meningitis develop hydrocephalus requiring VP shunt insertion.
- Seizures, lethargy, and leukopenia may indicate a higher risk for hydrocephalus in GBS meningitis.
- These findings highlight the importance of monitoring for hydrocephalus in infants with GBS meningitis.
Related Concept Videos
01:25Endocarditis I: Introduction
666
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
666
01:26Mitral Stenosis III: Medical Management
413
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
413
01:19Cranial and Spinal Meninges
4.6K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
4.6K
01:19Mitral Valve Prolapse III: Nursing Management
505
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
505
01:21Rheumatic Heart Disease III: Medical Management
451
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
451
01:23Rheumatic Heart Disease I: Introduction
735
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
735