Related Experiment Video
Updated: Mar 14, 2026

Establishment of Deep Hypothermic Circulatory Arrest in Rats
Published on: December 16, 2022
Severe accidental hypothermia treated with cardiopulmonary bypass
Mohammed Akil Dilawar Gani1, Balraj Singh Jagdev1, Asgher Champsi1
1UHCW, Coventry, UK.
Abstract:
This case report describes the successful treatment of severe accidental hypothermia with cardiopulmonary bypass (CPB). A known intravenous drug misuser aged 22 years was found to be unresponsive at his home (winter evening) with a Glasgow coma scale of 3/15. In the ambulance, the patient went into cardiac arrest, cardiopulmonary resuscitation being started. On arrival to the emergency department, he had a core body temperature of 27°C which was refractory to conservative management. He underwent femoro-femoral CPB, which was successful in rewarming the patient slowly. The patient was discharged home with no neurological deficit 10 days later.
Related Concept Videos
Decreased Body Temperature
Cardiopulmonary Resuscitation IV: Pharmacological Management
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:

