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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Multiple Eruptive Dermatofibromas Masquerading as Cutaneous Lymphoma.

Rowan Monteiro1, Vijay Aithal1, Rajalakshmi Tirumalae2

  • 1Department of Dermatology, St. John's Medical College and Hospital, Bengaluru, Karnataka, India.

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This study presents a rare case of multiple hemosiderotic histiocytomas, a variant of dermatofibroma, on a patient's lower limbs. Diagnosis was confirmed via biopsy and immunohistochemistry, with surgical excision recommended.

Keywords:
Hemosiderotic dermatofibromahistiocytomavimentin

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Area of Science:

  • Dermatology
  • Histopathology
  • Oncology

Background:

  • Multiple dermatofibromas are uncommon, with few documented cases.
  • Hemosiderotic histiocytoma is a rare variant of dermatofibroma.

Purpose of the Study:

  • To report a unique case of multiple hemosiderotic histiocytomas.
  • To highlight the diagnostic process and management of this rare condition.

Main Methods:

  • Clinical presentation of multiple firm to hard nodules on lower limbs.
  • Differential diagnosis including cutaneous lymphoma and dermatofibroma.
  • Biopsy and immunohistochemistry confirming hemosiderotic histiocytoma, positive for vimentin.

Main Results:

  • Histopathology confirmed hemosiderotic histiocytoma.
  • Immunohistochemistry showed positivity for vimentin.
  • The patient presented with multiple lesions predominantly on lower limbs.

Conclusions:

  • The occurrence of multiple hemosiderotic histiocytomas, a variant of dermatofibroma, has not been previously documented.
  • Surgical excision was advised for the patient's condition.