Effect of some anthelmintics on Hymenolepis nana in albino mice

Mebendazole and emetine (orally and parenterally) were used to treat mice infected with H. nana. Yomesan, in a single oral dose, was also used as a standardized well-known cesticidal drug. Emetine had a marked effect on cysticercoids leading to highly significant reduction in their number. Also, it caused complete removal of adult worms in infected mice. Mebendazole had no effect on the cysticercoid stage, but it caused significant reduction in the number of adult worms. Yomesan, showed a marked lethal effect on both the cysticercoids and adult worms leading to highly significant reduction in their number.