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Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Transmission-based Precautions II: Airborne and Protective Environment01:25

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
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Blood Transfusion01:15

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
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Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
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Transfusion Transmitted Infections in Armed Forces: Prevalence and Trends.

P K Gupta1, H Kumar2, D R Basannar3

  • 1Associate Professor, AFMC, Pune.

Medical Journal, Armed Forces India
|October 1, 2016
PubMed
Summary
This summary is machine-generated.

This study analyzed infectious markers in blood donors from 2000-2004. While some markers decreased, increased hepatitis C virus (HCV) and human immunodeficiency virus (HIV) seropositivity highlight the need for advanced screening to prevent transfusion-transmitted infections (TTI).

Keywords:
Hepatitis B virusHepatitis C virusHuman immunodeficiency virusTransfusion transmitted infections

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Area of Science:

  • Transfusion Medicine
  • Infectious Disease Epidemiology
  • Public Health

Background:

  • Prevalence of infectious disease markers in blood donors is crucial for transfusion safety.
  • Data from 2000-2004 in the Armed Forces blood transfusion service provides insights into trends.
  • Understanding donor demographics (voluntary vs. replacement) is key to interpreting marker prevalence.

Purpose of the Study:

  • To determine the prevalence of key infectious markers in voluntary and replacement blood donors.
  • To analyze trends in marker prevalence over a five-year period (2000-2004).
  • To inform strategies for reducing transfusion-transmitted infections (TTI).

Main Methods:

  • Screening of 39,646 blood units for hepatitis B surface antigen (HBsAg), HIV 1&2, HCV, and VDRL.
  • Categorization of donations into voluntary (61.9%) and replacement (38.1%).
  • Analysis of seropositivity rates over the study period.

Main Results:

  • Decreased prevalence of HBsAg and HIV in both donor groups.
  • Declining seropositivity for anti-HCV in voluntary donors, but an increase in replacement donors.
  • Overall seropositivity rates for HCV and HIV showed concerning trends in replacement donors.

Conclusions:

  • Advanced screening methods like nucleic acid amplification testing (NAT) for HCV and HIV, and anti-HBcAg (IgM) for HBV are recommended.
  • Financial constraints in developing countries may limit the implementation of advanced testing.
  • Strict donor selection criteria and sensitive laboratory screening remain vital for TTI reduction in India.