Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

15.4K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
15.4K
Disorders of Hemostasis01:24

Disorders of Hemostasis

2.6K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.6K
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

2.7K
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
2.7K
Overview of Hematopoiesis01:20

Overview of Hematopoiesis

11.0K
Hematopoiesis, or blood cell production, is a vital biological process that begins early in embryonic development and continues throughout life. This process generates the various types of cells found in blood, including red blood cells, white blood cells, and platelets from hematopoietic stem cells (HSCs).
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
11.0K
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

876
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
876
Hematopoiesis01:21

Hematopoiesis

9.6K
The process of blood cell formation is called hematopoiesis. Hematopoiesis starts early during development, on the seventh day of embryogenesis. This phase of hematopoiesis is called the primitive wave, wherein the extraembryonic yolk sac allows the production of erythroid cells and endothelial cells from a common precursor called hemangioblast. The erythroid cells provide oxygen to support the growth of the rapidly dividing embryo. Hemangioblasts later develop into hematopoietic stem cells or...
9.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.

Cell death & disease·2024
Same author

COVID-19 Stroke Apical Lung Examination Study 2: a national prospective CTA biomarker study of the lung apices, in patients presenting with suspected acute stroke (COVID SALES 2).

NeuroImage. Clinical·2024
Same author

The Effect of Surgical Weight Loss on Cognition in Individuals with Class II/III Obesity.

The journal of nutrition, health & aging·2023
Same author

Non-communicable diseases and their impact on depression, anxiety, and stress among the geriatric population residing in old age homes in Chennai, Tamil Nadu.

Journal of family medicine and primary care·2023
Same author

Physico-chemical and tribological properties of commercial oil - bio-lubricant mixtures dispersed with graphene nanoplatelets.

RSC advances·2023
Same author

Role of Reflux Symptom Index and Reflux Finding Score in Diagnosing Laryngopharyngeal Reflux: A Prospective Study.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India·2023

Related Experiment Video

Updated: Mar 14, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

7.2K

Dengue: A Clinicohaematological Profile.

M Banerjee1, T Chatterjee2, G S Choudhary3

  • 1Reader (Department of Biochemistry) AFMC, Pune.

Medical Journal, Armed Forces India
|October 1, 2016
PubMed
Summary
This summary is machine-generated.

A study found that 54% of suspected dengue fever cases were confirmed by enzyme-linked immunosorbent assay (ELISA). Fever with rash was common, but thrombocytopenia was infrequent, and one patient died from dengue shock syndrome (DSS).

Keywords:
Dengue haemorrhagic feverDengue shock syndromeThrombocytopenia

More Related Videos

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

2.2K
Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination
15:25

Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination

Published on: July 4, 2007

19.2K

Related Experiment Videos

Last Updated: Mar 14, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

7.2K
Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

2.2K
Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination
15:25

Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination

Published on: July 4, 2007

19.2K

Area of Science:

  • Infectious Diseases
  • Virology
  • Clinical Medicine

Background:

  • Studied fifty cases of fever with clinical suspicion of dengue.
  • Investigated clinical and hematological features of suspected dengue cases.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of IgM capture assay for dengue.
  • To identify common clinical manifestations and hematological findings in dengue patients.
  • To assess the incidence of severe dengue, including dengue shock syndrome (DSS).

Main Methods:

  • Conducted complete clinical and hematological evaluations.
  • Utilized IgM capture enzyme-linked immunosorbent assay (ELISA) for serological confirmation.
  • Analyzed clinical features, platelet counts, and patient outcomes.

Main Results:

  • 54% of suspected dengue cases tested positive for IgM antibodies via ELISA.
  • Fever with rash was the most frequent symptom, observed in 85% of patients.
  • Thrombocytopenia occurred in only 19% of cases; one fatality due to dengue shock syndrome (DSS) was recorded.

Conclusions:

  • Confirms the utility of IgM ELISA in diagnosing dengue, with 54% of clinically suspected cases being seropositive.
  • Highlights that fever with rash is a predominant clinical feature.
  • Suggests that thrombocytopenia is not a universal indicator of dengue infection, as evidenced by its low prevalence in this cohort and one fatality from DSS.