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The Prevalence of MRSA Nasal Carriage in Preoperative Pediatric Orthopaedic Patients

J J Walrath1, W L Hennrikus2, C Zalonis3

  • 1Department of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT, USA.

Advances in Orthopedics
|October 1, 2016
PubMed

Insights

Methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage is prevalent in pediatric orthopaedic patients. MRSA carriers face a significantly higher risk of developing postoperative surgical site infections (SSIs).

Area of Science:

  • Infectious Disease
  • Orthopaedic Surgery
  • Pediatric Health

Background:

  • Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) is a known risk factor for postsurgical infections.
  • Understanding MRSA prevalence in pediatric orthopaedic settings is crucial for infection control.

Purpose of the Study:

  • To determine the prevalence of MRSA nasal carriage in pediatric orthopaedic patients.
  • To assess if MRSA carrier status predicts postoperative surgical site infections (SSIs).

Main Methods:

  • Prospective screening for MRSA nasal carriage in 699 pediatric patients prior to orthopaedic surgery.
  • Review of postoperative cultures, SSIs, and patient data.

Main Results:

  • MRSA prevalence was 6.29% (44 of 699 patients).
  • Patients positive for MRSA had a significantly higher SSI rate (20.5%) compared to MRSA-negative patients (1.52%, p < 0.05).
  • All patients who developed SSIs were carriers of MRSA and had myelomeningocele.

Conclusions:

  • MRSA nasal carriage is a significant predictor of postoperative infection in pediatric orthopaedic patients.
  • Children with myelomeningocele are at elevated risk for MRSA carriage and subsequent SSIs.

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