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Cutaneous Melanoma in Asians.
1Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
Chonnam Medical Journal
|October 1, 2016
Summary
Acral lentiginous melanoma (ALM) is the most common skin cancer in Asians and not linked to UV exposure. Early detection of ALM, which presents on palms, soles, and nails, is crucial for reducing mortality.
Area of Science:
- Dermatology
- Oncology
Background:
- Malignant melanoma, though rare in Asians, is an aggressive skin cancer.
- Four main subtypes exist: lentigo maligna melanoma, superficial spreading melanoma, acral lentiginous melanoma (ALM), and nodular melanoma.
- UV radiation is a primary risk factor, except for ALM.
Purpose of the Study:
- To enhance understanding of cutaneous melanoma in Asians.
- To improve early detection rates for acral lentiginous melanoma.
- To reduce mortality associated with melanoma in Asian populations.
Main Methods:
- This is a brief review.
- The review focuses on understanding ALM presentation and risk factors.
- It aims to improve diagnostic accuracy.
Main Results:
- Acral lentiginous melanoma (ALM) is the most frequent melanoma subtype in Asians.
- ALM occurs on palms, soles, and nails, presenting as irregular maculopatches, nodules, or ulcers.
- Amelanotic ALM lacks pigment, increasing misdiagnosis risk as benign conditions.
Conclusions:
- Early detection of ALM is vital for improving outcomes in Asian patients.
- Recognizing ALM's unique characteristics, especially non-UV association and presentation, is key.
- Improved diagnostic awareness can significantly reduce melanoma mortality in Asians.
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