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Carcinomas ex monomorphic adenoma of salivary glands
M A Luna1, J G Batsakis, M E Tortoledo
1Department of Pathology, University of Texas, M. D. Anderson Cancer Center 77030.
The Journal of Laryngology and Otology
|August 1, 1989
Abstract:
A clinicopathological analysis of eight examples of carcinomas arising from salivary gland monomorphic adenomas, carcinomas ex monomorphic adenoma, is presented. These uncommon to rare neoplasms have a predilection for the parotid glands, are diagnosed about a decade later than their benign precursors, and most often arise from the dermal analogue type of monomorphic adenoma. As judged by follow-up periods of two to 16 years, carcinomas ex monomorphic adenoma are locally aggressive neoplasms with the clinical course marred by recurrences but without regional or distant metastases.