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Empirical modeling of metabolic alkalosis induced by sodium bicarbonate ingestion
Simon Green1,2, Jason C Siegler1
1a School of Science and Health, Western Sydney University, Sydney 2751, Australia.
Abstract:
Biphasic responses of blood HCO3- concentration and H+ concentration following ingestion of 3 doses of NaHCO3 (0.1, 0.2, 0.3 g·kg-1) were assessed in 8 men. For HCO3- concentration, there were significant effects of dose on maximum responses and timing, as well amplitudes, onsets, and/or time constants of phases 1 and 2. Fewer significant effects of dose were observed for H+ concentration and additional data demonstrated differential effects of dose on HCO3- concentration and H+ concentration responses and underlying phases.
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