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Ultrastructure of salivary calculi
Scandinavian Journal of Dental Research
|May 1, 1978
Summary
Submandibular salivary calculi exhibit diverse morphologies, with cellular debris and bacteria contributing to their organic matrix. Microscopic analysis reveals mineralized structures and spheroid bodies within these salivary stones.
Area of Science:
- Oral Pathology
- Biomineralization
- Microscopy
Background:
- Submandibular salivary calculi, or stones, are a common cause of salivary gland obstruction and pain.
- Previous research has focused on the chemical composition of salivary calculi, but their detailed microstructural organization remains less understood.
Purpose of the Study:
- To investigate the microstructural morphology of submandibular salivary calculi using light and electron microscopy.
- To identify the organic components and their potential origins within the calculi.
Main Methods:
- Examination of 21 submandibular salivary calculi from 19 patients using light and electron microscopy.
- Analysis of the mineralized matrix, cellular components, and associated structures.
Main Results:
- Calculi displayed extensive morphological variations, including lamellated patterns due to crystal incidence and dense homogeneous areas.
- Peripheral regions showed metaplastic squamous epithelium, connective tissue, disintegrated cellular substances, lipid-like granules, and bacteria (cocci, coliforms).
- Central parts contained spheroid bodies (1-100µm) of low electron density within an amorphous matrix.
Conclusions:
- The organic matrix of salivary calculi is formed from disintegrated cellular substances from adjacent tissues and potentially degenerated bacteria.
- The diverse morphology reflects variations in crystal deposition and the incorporation of organic debris.