Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

53.2K
Overview
53.2K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.5K
Factors Affecting Illness01:18

Factors Affecting Illness

5.6K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Factors Influencing Frequency of Pediatric Clinically Distinguishable Influenza: A 2 Season Case-Control Study.

Clinical medicine insights. Pediatrics·2022
Same author

Factors Affecting Vaccination in Children and Their Siblings After Autism Spectrum Disorder Diagnosis.

JAMA pediatrics·2018
Same author

Reasons for influenza vaccination underuse: A case-control study.

American journal of infection control·2017
Same author

Nutrition and Autism: Intervention Compared with Identification.

Advances in nutrition (Bethesda, Md.)·2016
Same author

Fatal Neonatal Herpes Simplex Infection Likely from Unrecognized Breast Lesions.

Journal of human lactation : official journal of International Lactation Consultant Association·2015
Same author

Interaction of genes and nutritional factors in the etiology of autism and attention deficit/hyperactivity disorders: a case control study.

Medical hypotheses·2014

Related Experiment Video

Updated: Mar 14, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
05:21

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

Published on: August 14, 2019

26.2K

Reasons for influenza vaccination underutilization: A case-control study.

Scott S Field1

  • 1Pediatric Department, Huntsville Hospital, Huntsville, AL; School of Medicine, University of Alabama, Birmingham, Huntsville, AL.

American Journal of Infection Control
|October 4, 2016
PubMed
Summary

Influenza vaccines are underused, with parents often citing a lack of perceived need. Prior influenza infection may increase risk, and live attenuated vaccines showed better performance than inactivated ones.

Keywords:
EfficacyInfluenzaInnate resistanceVaccine

More Related Videos

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.7K
An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers
06:34

An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers

Published on: December 1, 2017

38.3K

Related Experiment Videos

Last Updated: Mar 14, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
05:21

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

Published on: August 14, 2019

26.2K
Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.7K
An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers
06:34

An Optimized Hemagglutination Inhibition HI Assay to Quantify Influenza-specific Antibody Titers

Published on: December 1, 2017

38.3K

Area of Science:

  • Pediatric Infectious Diseases
  • Vaccinology
  • Public Health

Background:

  • Influenza vaccination rates remain suboptimal, despite the availability of effective vaccines.
  • Understanding parental attitudes and reasons for vaccine hesitancy is crucial for improving uptake.

Purpose of the Study:

  • To investigate the reasons behind influenza vaccine underutilization in a pediatric population.
  • To identify factors associated with influenza infection and vaccine effectiveness.

Main Methods:

  • A study enrolled pediatric patients tested for influenza during the 2012-2013 season.
  • Data on vaccination history, past influenza, and attitudes were collected via medical records and questionnaires.
  • Influenza-positive cases were compared with influenza-negative cases and controls to analyze risk factors and vaccine preferences.

Main Results:

  • Lack of perceived need was the most common reason for parental refusal of influenza vaccination.
  • A history of previous influenza infection was significantly associated with current disease (P < .0001).
  • Live attenuated influenza vaccine showed higher rates in controls compared to influenza patients, unlike injectable vaccines.

Conclusions:

  • Prior influenza infection may be a risk factor, potentially influencing the perceived benefit of vaccination.
  • Live attenuated influenza vaccine demonstrated superior performance compared to trivalent inactivated influenza vaccine.
  • Limited prior disease exposure and vaccine efficacy limitations may partially explain vaccine underutilization.