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Updated: Mar 14, 2026

Author Spotlight: Exploring Plasticity of Sympathetic Neurons
Published on: July 5, 2024
The History of Sympathetic Surgery
1Department of Surgery, Rambam Medical Center & Faculty of Medicine, Technion - Israel Institute of Technology, PO Box 359, Zikhron Ya'akov, Haifa 3095202, Israel.
Abstract:
At present, primary hyperhidrosis is the main indication for sympathectomy. For upper thoracic sympathetic ablation, excision of the second thoracic ganglion alone or with the first and/or third ganglia was the standard during the open surgery era. With the advent of thoracoscopy, modifications related to the level, extent, and type of ablation were proposed to attenuate compensatory hyperhidrosis. The ideal operation for sympathetic denervation of the face and upper limbs remain to be defined. Controlled double-blind studies with quantitave measurements of sweat production are required.
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