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High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication
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Drug Repurposing: New Treatments for Zika Virus Infection?
Feixiong Cheng1, James L Murray2, Donald H Rubin3
1Center for Complex Networks Research, Northeastern University, Boston, MA 02115, USA; Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Trends in Molecular Medicine
|October 4, 2016
Abstract:
To date, no antiviral agents have been approved for treating Zika virus (ZIKV) infection. Two recent drug-repurposing studies published in Cell Host & Microbe and Nature Medicine demonstrated that screening FDA-approved drugs for antiviral activity is a promising strategy for identifying therapeutics with novel activity against ZIKV infection.
