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Interim PET Scans in Diffuse Large B-Cell Lymphoma: Is It Ready for Prime Time?

Maital Bolshinsky1, Chadi Nabhan2

  • 1Instituto Oncologico Veneto, Padua, Italy.

Clinical Lymphoma, Myeloma & Leukemia
|October 4, 2016
PubMed

Prognostication of patients with diffuse large B-cell lymphoma (DLBCL) has improved in the past decade with a variety of clinical, morphologic, molecular, and radiographic methods. Comparable to data on the value of interim positron emission tomography (I-PET) in Hodgkin lymphoma, several retrospective and prospective studies are attempting to assess the value of I-PET scanning in DLBCL patients. In this review, we briefly describe and analyze the various prognostic methods in DLBCL with specific focus on the value of I-PET scanning in this disease. This is a timely analysis, as tailoring therapies based on prognosis at diagnosis are becoming of increased investigational interest.

Keywords:
Interim imagingLarge-cell lymphomaLymphomaPET scanningPrognosis

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