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Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging
Published on: June 21, 2011
Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles
Aoife Kilcoyne1, Mukesh G Harisinghani1, Umar Mahmood2
1Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.
Abstract:
Over the last 2 decades, the use of nanoparticle imaging has been investigated extensively for both diagnosis and therapy of prostate cancer. This review discusses the various classes of nanoparticles currently in clinical use or at the advanced preclinical stage. In particular, we focus on the unique properties of nanoparticles, as a group, that make them suitable for imaging and therapy. The characteristics of each nanoparticle are detailed. Iron oxide nanoparticles, extensively used for MRI of prostate cancer, are discussed in depth.

