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Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

2.6K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
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Assessment of the Mouth01:26

Assessment of the Mouth

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A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
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Oral Cavity01:11

Oral Cavity

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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Therapies02:49

Cancer Therapies

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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Related Experiment Video

Updated: Mar 14, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
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Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

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Cancer and orofacial pain.

M Romero-Reyes1, D Salvemini

  • 1Department of Oral & Maxillofacial, Pathology, Radiology & Medicine, New York University College of Dentistry, 345 East 24th Street, New York, NY 10010, mrr7@nyu.edu.

Medicina Oral, Patologia Oral Y Cirugia Bucal
|October 4, 2016
PubMed
Summary

Orofacial pain can be an early or late symptom of cancer, requiring careful differential diagnosis. Understanding cancer pain mechanisms is crucial for developing better therapeutic options.

Area of Science:

  • Oncology
  • Pain Medicine
  • Oral Medicine

Background:

  • Orofacial pain can be a primary symptom of cancer or indicate advanced stages.
  • This review synthesizes information from a conference on orofacial pain and cancer.

Purpose of the Study:

  • To comprehensively review cancer-associated orofacial pain.
  • To discuss mechanisms, cancer types, and therapeutic advancements.

Main Methods:

  • Literature review of PubMed-MEDLINE, including reviews, systematic reviews, and case studies.
  • Focused on evidence-based mechanisms, cancer types, and pain therapies.

Main Results:

  • Cancer pain pathophysiology remains poorly understood due to tumor heterogeneity.

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Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior
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Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

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  • Orofacial pain can result from regional/distant tumors or cancer therapy.

    • Conclusions:

    • Differential diagnosis is essential, as cancer pain can mimic other orofacial disorders.
    • Diagnosis requires excluding common etiologies; current treatments are suboptimal but improving.