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H Schneider1

  • 1Universitäts-Frauenklinik, Schanzeneckstrasse 1, CH-3012, Bern, Switzerland.

Archives of Gynecology and Obstetrics
|October 4, 2016
PubMed
Summary

Cerebral palsy (CP) prevalence is rising due to better survival of premature infants. Birth asphyxia is a minor cause in term infants, with perinatal events more significant for premature babies.

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Area of Science:

  • Neurology
  • Pediatrics
  • Obstetrics

Background:

  • Cerebral palsy (CP) prevalence has increased globally over 15 years.
  • Improved survival rates for very low birth weight premature infants contribute to this rise.
  • Birth asphyxia is a less significant cause of CP in term infants compared to premature deliveries.

Purpose of the Study:

  • To analyze the causes and contributing factors of cerebral palsy.
  • To differentiate the significance of birth asphyxia versus perinatal events in CP development.
  • To investigate the relationship between prenatal factors and CP outcomes.

Main Methods:

  • Review of epidemiological data on CP prevalence.
  • Analysis of risk factors associated with term and premature deliveries.
  • Evaluation of the role of birth asphyxia and perinatal events in CP etiology.

Main Results:

  • Birth asphyxia is implicated in only 10% of CP cases following term delivery.
  • Perinatal events are more significant for CP development in premature infants.
  • Severe oxygen deficit during the perinatal period is critical for long-term CP prognosis.
  • The causal link between severe birth asphyxia and psychomotor handicap is not definitively proven.
  • Prenatal brain damage or common pathologies may precede and cause both birth asphyxia and CP.

Conclusions:

  • The rising prevalence of cerebral palsy is linked to increased survival of extremely premature infants.
  • While birth asphyxia can contribute, perinatal factors are more crucial, especially in premature births.
  • Prenatal factors and common pathologies may be underlying causes for both brain damage and birth asphyxia, complicating direct causal attribution.
Keywords:
Birth asphyxiaCerebral palsyEtiology

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