Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

3.7K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
3.7K
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

7.7K
The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
7.7K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

10.0K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
10.0K
Introduction to Lymphatic and Immune System01:23

Introduction to Lymphatic and Immune System

18.9K
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born...
18.9K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

2.7K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
2.7K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

16.4K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
16.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Toxicological risk assessment using the example of potential contact sensitization to resorcinol].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2019
Same author

Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine in p-phenylenediamine highly allergic volunteers using allergy alert test: the Italian experience.

European annals of allergy and clinical immunology·2019
Same author

Continuous usage of a hair dye product containing 2-methoxymethyl-para-phenylenediamine by hair-dye-allergic individuals.

The British journal of dermatology·2016
Same author

Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine under hair dye use conditions in p-phenylenediamine-allergic individuals.

The British journal of dermatology·2014
Same author

Assessment of the elicitation response in subjects weakly sensitized to p-phenylenediamine.

The British journal of dermatology·2014
Same author

[Bilateral chronic dacryoadenitis].

Zeitschrift fur Rheumatologie·2013

Related Experiment Video

Updated: Mar 14, 2026

Murine Bilateral Renal Lymphadenectomy
06:20

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

130

[Lymphadenitis and systemic lupus erythematosus].

H Merwald-Fraenk1, F Wiesent2, R Dörfler3

  • 1Endokrinologikum München, Promenadeplatz 12, 80333, München, Deutschland. helga.merwald-fraenk@amedes-group.com.

Zeitschrift Fur Rheumatologie
|October 4, 2016
PubMed
Summary

A rare case of Kikuchi-Fujimoto disease, typically seen in Asian females, was diagnosed in a Caucasian patient. This case highlights the potential for co-occurrence with systemic lupus erythematosus (SLE).

Keywords:
FeverKikuchi-Fujimoto diseaseLymph node histologyLymphadenitisSystemic lupus erythematosus

More Related Videos

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

19.0K
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

3.6K

Related Experiment Videos

Last Updated: Mar 14, 2026

Murine Bilateral Renal Lymphadenectomy
06:20

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

130
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

19.0K
Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

3.6K

Area of Science:

  • Immunology
  • Pathology
  • Rheumatology

Background:

  • Kikuchi-Fujimoto disease (KFD) is a rare, benign condition causing lymphadenopathy, predominantly affecting young Asian females.
  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.

Observation:

  • A 25-year-old Caucasian female presented with fever and cervical lymphadenopathy.
  • Laboratory results revealed elevated inflammatory markers, a high antinuclear antibody (ANA) titer, and positive anti-double-stranded DNA (anti-dsDNA) antibodies.
  • Lymph node histopathology confirmed Kikuchi-Fujimoto disease.

Findings:

  • The patient's presentation, including serological markers (ANA, anti-dsDNA) and arthralgia, suggested a potential simultaneous diagnosis of SLE.
  • Histopathological findings were characteristic of KFD, despite the patient's Caucasian ethnicity, which is atypical for this condition.

Implications:

  • This case underscores the importance of considering KFD in patients with unexplained lymphadenopathy and autoimmune markers, irrespective of ethnicity.
  • The co-occurrence of KFD and SLE warrants further investigation into potential sharedpathogenic mechanisms.
  • Accurate diagnosis is crucial for appropriate management and to avoid misdiagnosis or unnecessary treatments.