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Low startle magnitude may be a behavioral marker of vulnerability to cocaine addiction
Marina G Wheeler1,2, Erica Duncan3,4, Michael Davis1,2,4
1Department of Psychology, Emory University, 201 Dowman Drive, Atlanta, Georgia 30322.
Synapse (New York, N.Y.)
|October 4, 2016
Abstract:
Cocaine addicted men have low startle magnitude persisting during prolonged abstinence. Low startle rats show greater cocaine self-administration than high startle rats. Low startle may be a marker of a vulnerability to heightened cocaine-related behaviors in rats and similarly may be a marker of vulnerability to cocaine addiction in humans.
