Related Experiment Video
Updated: Mar 14, 2026

Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing
Published on: February 13, 2016
Biofouling in forward osmosis systems: An experimental and numerical study
Szilárd S Bucs1, Rodrigo Valladares Linares1, Johannes S Vrouwenvelder2
1King Abdullah University of Science and Technology (KAUST), Water Desalination and Reuse Center (WDRC), Division of Biological and Environmental Science and Engineering (BESE), Thuwal 23955-6900, Saudi Arabia.
Biofouling significantly impacts forward osmosis (FO) membrane performance by increasing external concentration polarization. Biofilm properties and location critically affect water flux, with draw channel fouling being more detrimental.
Area of Science:
- Membrane Science and Engineering
- Biotechnology
- Environmental Engineering
Background:
- Biofouling is a major challenge in membrane processes, reducing efficiency and increasing operational costs.
- Forward Osmosis (FO) systems are susceptible to performance degradation due to biofilm formation on membrane surfaces.
- Understanding the mechanisms of biofouling is crucial for developing effective mitigation strategies.
Purpose of the Study:
- To numerically simulate and experimentally validate the impact of biofouling on cross-flow forward osmosis (FO) system performance.
- To investigate the influence of biofilm characteristics (thickness, permeability, porosity, coverage) and location on FO process parameters.
- To identify key factors contributing to performance loss caused by biofouling.
Main Methods:
- Development of a two-dimensional numerical model coupling fluid flow, solute transport, and biofilm dynamics.
- Validation of the numerical model against experimental data under various osmotic conditions and batch operations.
- Exploration of biofilm properties and location effects on salt external concentration polarization and water flux.
Main Results:
- Biofouling significantly increases external concentration polarization in FO systems.
- Biofilm hydraulic permeability and membrane surface coverage are the most influential factors on water flux reduction.
- Biofilm formation in the draw channel has a greater negative impact on FO performance than in the feed channel.
Conclusions:
- The developed mathematical model provides insights into biofouling mechanisms in FO systems.
- Biofilm properties and location are critical determinants of performance loss in FO.
- This study aids in developing strategies for biofouling control and mitigation in FO membrane applications.
Related Concept Videos
Osmosis and Osmotic Pressure of Solutions
Typical Model Studies
Osmotic Pressure
Osmosis
Water, like other substances, moves from a high concentration of...
Osmoregulation in Fishes
Modeling and Similitude

