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An extreme case of platypnoea-orthodeoxia syndrome
Kevin O'Gallagher1, Evelyn Chou2, Swarna Jeyabraba2
1specialty registrar in interventional cardiology, King's College Hospital NHS Foundation Trust, London, UK drkogallagher@gmail.com.
Abstract:
An 80-year-old female presented with progressive breathlessness, worse on sitting or standing and relieved by lying flat. Subsequent investigations identified a patent foramen ovale (PFO) with right-to-left flow across the interatrial septum (IAS). A diagnosis of platypnoea orthodeoxia syndrome secondary to inter-atrial shunting was made. Technical features precluded a percutaneous PFO closure so an open surgical repair was performed with complete resolution of symptoms. We discuss the pathophysiology and management of platypnoea orthodeoxia syndrome.
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