Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Status of Alzheimer's and Parkinson's Disease Detections and Treatments.

ACS chemical neuroscience·2026

Same author

Dynamics of Aβ42 Tetramer by REST2-CHARMM36m Simulations.

The journal of physical chemistry. B·2026

Same author

Unveiling the entropic role of hydration water in SOD1 partitioning within FUS condensate.

The Journal of chemical physics·2026

Same author

Cytoplasmic fluidity and the cold life: proteome stability is decoupled from viability in psychrophiles.

Nature communications·2025

Same author

Unraveling the Link Between Thermal Adaptation and Latent Allostery in Malate Dehydrogenase From Methanococcales.

Journal of molecular biology·2025

Same author

Varoglutamstat Inhibits the Dimerization of the Aβ<sub>25-35</sub> Fragment in Aqueous Solution.

The journal of physical chemistry. B·2025

Same journal

Inverse FIP effect plasma in the solar atmosphere: a synthesis of current understanding and new insights from AR 11967.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026

Same journal

Signs of sulfur fractionation under high magnetic field strength.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026

Same journal

First ionization potential fractionation of sulfur observed with spectral imaging of the coronal environment.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026

Same journal

Chromospheric dynamics and turbulence regulate the solar FIP effect.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026

Same journal

Exploring the link between wave activity in the photospheric velocity driver and the FIP bias in the solar corona.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026

Same journal

Radiative hydrodynamic simulations of first ionization potential fractionation in solar flares.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 14, 2026

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

Multiscale simulation of molecular processes in cellular environments.

Mara Chiricotto¹, Fabio Sterpone¹, Philippe Derreumaux¹

¹Laboratoire de Biochimie Théorique, UPR 9080 CNRS, Université Paris Diderot, Sorbonne Paris Cité, IBPC, 13 Rue Pierre et Marie Curie, 75005 Paris, France.

Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences

|October 5, 2016

Summary

This summary is machine-generated.

New multiscale simulation methods enable the study of large biological systems. This dual technique accurately models macromolecules and solvents, advancing biosimulation capabilities.

Keywords:

cellular compartments lattice Boltzmann molecular dynamics multiscale

More Related Videos

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Published on: March 1, 2022

Related Experiment Videos

Last Updated: Mar 14, 2026

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics

Published on: April 12, 2019

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion

Published on: March 1, 2022

Area of Science:

Computational biology
Biophysics
Molecular modeling

Background:

Studying large biological systems requires advanced simulation techniques.
Existing methods face limitations in scale and accuracy for complex biosystems.

Purpose of the Study:

To present recent advances in multiscale simulations for biological systems.
To introduce a novel dual technique for enhanced biosimulation.

Main Methods:

Utilizing a coarse-grained representation for macromolecules.
Employing a mesoscopic description for the aqueous solvent.
Implementing a dual technique for particle-solvent interaction and force exchange.

Main Results:

Achieved a stable and accurate simulation methodology.
Enabled the simulation of biosystems at unprecedented sizes.
Demonstrated the efficacy of the dual technique in handling complex interactions.

Conclusions:

The developed multiscale simulation scheme offers significant advantages for studying large-scale biological systems.
This methodology enhances the accuracy and stability of biosimulations.
Opens new avenues for exploring complex biological phenomena at the physics-chemistry-biology interface.