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Pleomorphic Hyalinizing Angiectatic Tumor Arising in the Hand: A Case Report
Patrick M Kane1, Michael P Gaspar1, Benjamin B Whiting1
1The Philadelphia Hand Center, Philadelphia PA, USA.
Hand (New York, N.Y.)
|October 5, 2016
Summary
Pleomorphic hyalinizing angiectatic tumors (PHATs) are rare, non-metastasizing tumors. This report details the first documented case of PHAT occurring on the hand, highlighting its surgical management and pathology.
Area of Science:
- Orthopedic Oncology
- Surgical Pathology
- Rare Tumor Research
Background:
- Pleomorphic hyalinizing angiectatic tumors (PHATs) are exceptionally rare neoplasms of uncertain etiology.
- PHATs typically manifest in the lower extremities, with fewer than 100 cases reported globally since 1996.
- This tumor type is characterized by its non-metastasizing nature.
Observation:
- A 35-year-old male presented with a dorsal hand mass of several years' duration.
- The mass caused pain with power grasp and direct pressure prior to surgical excision.
- Surgical findings revealed the mass was adherent to the underlying extensor tendons.
Findings:
- Immunopathology confirmed the dorsal hand mass as a pleomorphic hyalinizing angiectatic tumor (PHAT).
- This represents the first documented instance of a PHAT occurring in the hand.
- The case underscores the importance of considering rare diagnoses in atypical locations.
Implications:
- This case expands the known anatomical distribution of PHATs.
- It highlights the need for thorough pre-operative evaluation and tailored surgical management for rare hand masses.
- Further research into PHATs' etiology and behavior is warranted, particularly in unusual sites.
