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Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
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Eyelid cleansing with ointment for obstructive meibomian gland dysfunction

Minako Kaido1,2, Osama M A Ibrahim3, Motoko Kawashima3

  • 1Department of Ophthalmology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan. fwiw1193@mb.infoweb.ne.jp.

Japanese Journal of Ophthalmology
|October 5, 2016
PubMed
Abstract

Insights

Ofloxacin ophthalmic ointment effectively cleans eyelid margins for obstructive meibomian gland dysfunction (MGD). This treatment improved MGD symptoms and tear stability in most patients.

Area of Science:

  • Ophthalmology
  • Ocular Surface Disease

Background:

  • Obstructive meibomian gland dysfunction (MGD) is a common condition affecting tear film stability.
  • Lid margin hygiene is crucial for managing MGD.

Purpose of the Study:

  • To evaluate the efficacy of eyelid margin cleansing using ofloxacin ophthalmic ointment in patients with obstructive MGD.

Main Methods:

  • 31 patients with obstructive MGD received daily eyelid margin cleansing with ofloxacin ointment for 3 months.
  • Lid margin abnormalities, meibum quality, and tear stability were assessed before and after treatment.
  • MGD symptom severity was evaluated using a questionnaire post-treatment.

Main Results:

  • Significant reductions in vascular engorgement, abnormal meibum, debris, and staining were observed.
  • Tear break-up time significantly improved post-treatment (p < 0.05).
  • 86.2% of patients reported improvement in MGD symptoms.

Conclusions:

  • Eyelid margin cleansing with ofloxacin ophthalmic ointment shows promise as an effective treatment for obstructive MGD.
  • This intervention may help alleviate symptoms and improve ocular surface parameters in MGD patients.
Keywords:
Dry eyeLid hygieneMeibomian gland dysfunctionMeibumTear stability

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