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Updated: Mar 14, 2026

HKUST-1 as a Heterogeneous Catalyst for the Synthesis of Vanillin
Published on: July 23, 2016
Click inspired synthesis of triazole-linked vanillin glycoconjugates
Pratibha Dwivedi1,2, Kunj B Mishra1, Pritika2
1Department of Chemistry, Centre of Advanced Study, Faculty of Science, Banaras Hindu University, Varanasi, -221005, India.
Abstract:
The 1,3-dipolar cycloaddition of deoxy-azido sugars 1 with alkyne derivatives of p-vanillin, 3-methoxy-4-(prop-2-ynyloxy)benzaldehyde (2) and 2-methoxy-1-(prop-2-ynyloxy)-4-((prop-2-ynyloxy)methyl)benzene) (4) to afford regioselective triazole-linked vanillinglycoconjugates 5 and 6 was investigated in the presence of CuI/DIPEA in dichloromethane. All the developed glycoconjugates were characterized on the basis of IR, NMR, and MS. Graphical abstract Triazolyl vanillin glycoconjugates via click chemistry.
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