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Effects of Antihypertensive Therapy on Blood Pressure Variability

Kazuo Eguchi1

  • 1Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, 329-0498, Japan. ke112@jichi.ac.jp.

Current Hypertension Reports
|October 5, 2016
PubMed

Insights

Antihypertensive therapy impacts blood pressure variability (BPV). Long-acting calcium channel blockers may reduce BPV, while adherence is key for better outcomes in hypertension management.

Area of Science:

  • Cardiology
  • Hypertension Research

Background:

  • Blood pressure variability (BPV) is linked to target organ damage and cardiovascular prognosis.
  • Visit-to-visit BP variability predicts cardiovascular events in treated hypertensive patients.

Purpose of the Study:

  • To summarize the effects of antihypertensive therapy on different types of blood pressure variability in hypertensive individuals.

Main Methods:

  • Literature review summarizing existing studies on antihypertensive therapy and BPV.
  • Analysis of BPV markers including visit-to-visit, day-by-day, and ambulatory BPV.

Main Results:

  • Long-acting calcium channel blockers (CCBs) show potential in reducing BPV.
  • Medication non-adherence significantly contributes to increased BPV.
  • BPV reduction may be a crucial strategy for high-risk patients.

Conclusions:

  • While BPV is not a direct target for antihypertensive treatment due to limited evidence, its reduction is clinically significant for high-risk patients.
  • Improving adherence to antihypertensive medication is vital for favorable prognosis.
Abstract

Keywords:
Antihypertensive therapyBPVBlood pressureVariability in blood pressure

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