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Epigenetic control of the tumor microenvironment.

David L Marks1, Rachel Lo Olson1,2, Martin E Fernandez-Zapico1

  • 1Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

Epigenomics
|October 5, 2016
PubMed
Summary

Epigenetic mechanisms like DNA methylation and histone modifications regulate tumor microenvironment stromal cells. Understanding these epigenetic changes offers new therapeutic strategies for cancer treatment.

Keywords:
DNA and histone methyltransferasesDNA methylationcancer-associated fibroblastschromatin dynamicsendothelial cellsgene expressionhistone deacetylaseshistone marksimmune cellsnoncoding RNAs

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