Related Experiment Videos
Reversed effects between crude and processed ginger extracts on PGF2 alpha-induced contraction in mouse mesenteric
1Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan.
Japanese Journal of Pharmacology
|June 1, 1989
Abstract:
The effects of crude and processed ginger extracts and pungent components, S-(+)-[6]-gingerol and [6]-shogaol, on noradrenaline (NA)- and prostaglandin (PG) F2 alpha-induced contraction were investigated using mouse mesenteric veins. Both spicy constituents inhibited the contractile responses to NA. Crude ginger extract and S-(+)-[6]-gingerol potentiated the PGF2 alpha-induced contraction, whereas processed ginger extract and [6]-shogaol inhibited the contraction.