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Related Experiment Videos

High current pulser for transmural and field stimulation.

D F Biggs1, C Ediss

  • 1Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.

Journal of Pharmacological Methods
|August 1, 1989
PubMed
Summary

This study details a low-resistance constant current pulse generator for stimulating biological tissues. Direct measurement of current and voltage is the optimal method for monitoring stimulation parameters.

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Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Physiology

Background:

  • Accurate stimulation of biological tissues requires precise control over electrical parameters.
  • Existing methods may not adequately provide the high currents needed for transmural and field stimulation.

Purpose of the Study:

  • To outline the requirements and design of a constant current pulse generator.
  • To develop a generator with low internal resistance for high-current output.
  • To establish optimal methods for monitoring stimulation parameters.

Main Methods:

  • Design and construction of a constant current pulse generator.
  • Characterization of generator's internal resistance and current output capabilities.
  • Evaluation of direct current and voltage measurement for parameter monitoring.

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Main Results:

  • A constant current pulse generator with low internal resistance was successfully designed.
  • The generator is capable of delivering high currents necessary for tissue stimulation.
  • Direct measurement of current and voltage proved effective for monitoring.

Conclusions:

  • The designed pulse generator meets the requirements for biological tissue stimulation.
  • Direct measurement of current and voltage is the most reliable method for monitoring stimulus parameters during transmural and field stimulation.