Gemstone spectral imaging for measuring adult bone mineral density

The present study aimed to detect the bone Ca²⁺ content of L3 vertebrae in adults by gemstone spectral computed tomography. In total, 235 patients were selected and divided into age groups of 10 years each. The scanning data were used to detect the water-based and Ca²⁺-based substance levels on the L3 vertebral cancellous bone images. The results indicated that there were significant differences in vertebral Ca²⁺-water and water-Ca²⁺ densities determined by gemstone spectral imaging (GSI) between males and females in subjects aged 50-59 years, 60-69 years, 70-79 years and ≥80 years (P<0.05). The ages of male and female participants were negatively correlated with vertebral Ca²⁺-water density (P<0.01) and water-Ca²⁺ density (P<0.01). In conclusion, GSI may be used as a novel method of measuring the vertebral adult bone mineral density.