Related Experiment Video
Updated: Mar 14, 2026

11:20
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
4.5K
Vitrectomy for bilateral macular schisis without apparent optic disc anomalies
José Andonegui1, José Ramón Maya2, Marta Echeverría1
1Department of Ophthalmology, Complejo Hospitalario de Navarra, Pamplona, Spain.
GMS Ophthalmology Cases
|October 6, 2016
Summary
This study presents a case of bilateral macular schisis treated successfully with vitrectomy. The findings suggest vitrectomy is a viable option for visual acuity improvement in such cases.
Area of Science:
- Ophthalmology
- Retinal Diseases
Background:
- Macular schisis, characterized by fluid accumulation in retinal layers, can cause visual acuity loss.
- While often associated with optic disc anomalies, its occurrence without apparent disc issues is noted.
Observation:
- A 78-year-old male presented with bilateral visual acuity loss.
- Optical coherence tomography revealed bilateral macular schisis with external retinal fluid accumulation, notably without vitreous traction.
- Standard fundus examination and fluorescein angiography were unremarkable.
Findings:
- Both eyes underwent phacoemulsification, intraocular lens implantation, and vitrectomy, omitting laser, gas, or fenestration.
- A slow, progressive resorption of fluid and improvement in visual acuity (VA) were observed post-procedure.
Implications:
- Macular schisis may occur in patients lacking apparent optic disc anomalies.
- Vitrectomy, even without adjunctive procedures like laser or gas, demonstrates therapeutic potential for visual recovery in macular schisis, even with preoperative posterior vitreous detachment (PVD).
Related Concept Videos
Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment
1.5K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.5K

