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Updated: Mar 14, 2026

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
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HIV Triggers a cGAS-Dependent, Vpu- and Vpr-Regulated Type I Interferon Response in CD4+ T Cells

Jolien Vermeire1, Ferdinand Roesch2, Daniel Sauter3

  • 1Department of Clinical Chemistry, Microbiology, and Immunology, Ghent University, 9000 Ghent, Belgium.

Cell Reports
|October 6, 2016
PubMed

Keywords:
CD4HIVNF-κBT cellsVprVpucGASdendritic cellsinnate sensinginterferon

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