Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients

Area of Science:

• Endocrinology
• Neurology
• Urology

Background:

• Diabetes mellitus (DM) is a chronic metabolic disorder with numerous potential complications.
• Diabetic polyneuropathy and hyperactive bladder syndrome (OAB) are two such common complications.
• Early detection and correlation of these complications are crucial for patient management.

Purpose of the Study:

• To investigate the correlation between hyperactive bladder syndrome (OAB) and diabetic polyneuropathy.
• To assess the relationship between OAB and other microvascular complications like retinopathy and nephropathy in diabetic patients.
• To evaluate the utility of noninvasive screening tests for diagnosing these DM complications.

Main Methods:

• A prospective study involving 120 type 2 diabetic patients (80 female, 40 male).
• Diabetic polyneuropathy assessed using the Douleur Neuropathique 4 Questions (DN4) screening tool.
• Overactive bladder (OAB) assessed using the Overactive Bladder Questionnaire (OAB-V8) screening tool.
• Patients were also evaluated for retinopathy and nephropathy.

Main Results:

• A significant positive correlation was found between OAB and diabetic polyneuropathy in both female and male patients (P<0.05).
• No significant correlations were observed between OAB and retinopathy or nephropathy in either gender (P>0.05).
• The study highlights a strong association between OAB and polyneuropathy in diabetic individuals.

Conclusions:

• Hyperactive bladder syndrome (OAB) and diabetic peripheral neuropathy are significantly correlated in patients with diabetes mellitus.
• These correlations can be effectively identified using simple, valid, and reliable noninvasive screening tests.
• Neurologists and urologists can utilize these screening tools for early diagnosis and management of these common diabetic complications.