Abnormal eye movements in three types of chorea
Tiago Attoni1, Rogério Beato2, Serge Pinto3
1Universidade Federal de Minas Gerais, Programa de Pós-Graduação em Neurociências, Belo Horizonte MG, Brasil.
Arquivos De Neuro-Psiquiatria
|October 6, 2016
Summary
Chorea, characterized by involuntary muscle movements, often involves basal ganglia dysfunction. This review examines abnormal eye movements in Sydenham
Area of Science:
- Neurology
- Ophthalmology
Background:
- Chorea is an involuntary movement disorder stemming from basal ganglia dysfunction.
- Basal ganglia are crucial for controlling eye movements.
- Ocular motor abnormalities are frequently observed in choreiform disorders.
Purpose of the Study:
- To review the primary characteristics of eye motion in three specific basal ganglia disorders associated with chorea.
- To highlight the relationship between basal ganglia dysfunction and altered ocular motor control in chorea.
Main Methods:
- Literature review focusing on Sydenham's chorea, Huntington's disease, and neuroacanthocytosis.
- Analysis of studies reporting ocular motor findings in these conditions.
- Examination of saccade tasks, slow pursuit, target setting, and anti-saccade tasks.
Main Results:
- Abnormalities in saccadic eye movements are characteristic of these basal ganglia diseases.
- Impaired smooth pursuit and difficulties with target acquisition and anti-saccade tasks are noted.
- Ocular motor deficits correlate with the extent of basal ganglia dysfunction.
Conclusions:
- Altered eye movements are a significant clinical feature in Sydenham's chorea, Huntington's disease, and neuroacanthocytosis.
- Ocular motor testing can aid in the diagnosis and understanding of basal ganglia disorders.
- Further research into the neurophysiological basis of these eye movement abnormalities is warranted.
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