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Updated: Mar 14, 2026

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
Pain characterization in Duchenne muscular dystrophy.
Talita Dias da Silva1, Thais Massetti1,2, Carlos Bandeira de Mello Monteiro2
1Universidade Federal de São Paulo, Faculdade de Medicina, Departamento de Cardiologia, São Paulo SP, Brasil.
Pain is a common issue for individuals with Duchenne Muscular Dystrophy (DMD). This systematic review highlights that pain significantly impacts their quality of life and is a manageable symptom.
Area of Science:
- Neurology
- Pediatrics
- Pain Management
Background:
- Duchenne Muscular Dystrophy (DMD) is a severe genetic disorder characterized by progressive muscle degeneration.
- Pain is a recognized but often under-addressed symptom in the DMD population.
Purpose of the Study:
- To systematically review the existing literature on the relationship between Duchenne Muscular Dystrophy and pain.
- To understand the prevalence and impact of pain in boys diagnosed with DMD.
Main Methods:
- A systematic literature search was conducted across Medline/PubMed and BVS databases.
- Keywords used included 'Muscular Dystrophy, Duchenne' and 'Pain'.
- Studies focusing on pain assessment in DMD patients were included.
Main Results:
- An initial search yielded 175 studies, with 167 excluded due to not meeting inclusion criteria.
- Eight eligible studies were analyzed for pain occurrence and characteristics in DMD.
- Pain was identified as a frequent symptom in the studied population.
Conclusions:
- Pain is a prevalent issue for individuals with Duchenne Muscular Dystrophy.
- Pain management is a potentially tractable aspect of care for this population.
- Pain directly influences the quality of life for individuals with DMD.
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