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Location of Acute Infarcts and Agitation and Aggression in Stroke
Wai Kwong Tang1, Xiang Xin Liu1, Huajun Liang1
1From the Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China (WKT, XXL, HJL); the Department of Neurology, Dongguan People's Hospital, Dongguan, Guangdong Province, P.R. China (YKC); the Department of Imaging & Interventional Radiology, Chinese University of Hong Kong, Hong Kong SAR, China (WCWC, ATA, JA); the Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China (VCTM, KSW); the University of Notre Dame Australia/Marian Centre, Perth, Australia and School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia (GSU); and the Neuropsychiatry Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina, Rome, Italy (GS).
Abstract:
The role of the infarct location in the development of poststroke agitation (PSA) is largely unknown. This study examined the association between the locations of infarcts and PSA at 9 months following the index stroke in 213 patients with the Chinese version of the Neuropsychiatric Inventory. Compared with the non-PSA group, PSA patients had a higher number and volume of acute pontine infarcts. Ventral pontine and lateral cerebellar infarcts were independent predictors of PSA in the multivariate analysis.
