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Factors Associated with Changes in Invasive and Noninvasive Positive Airway Pressure Therapy Settings during
Suhail Al-Saleh1,2, Priya Sayal2, Derek Stephens3
1Division of Respiratory Medicine, Hospital for Sick Children, Toronto, Canada.
Insights
Pediatric patients on positive airway pressure therapy are more likely to have their settings adjusted during polysomnography (PSG) if initiated recently, using bilevel positive airway pressure (BPAP), or having central nervous system/musculoskeletal diagnoses.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Respiratory Care
Background:
- Positive airway pressure (PAP) therapy is crucial for managing pediatric respiratory conditions.
- Polysomnography (PSG) with technology titration is essential for optimizing PAP settings.
- Efficient allocation of PSG resources is vital due to limited availability.
Purpose of the Study:
- To identify clinical predictors of setting changes during positive airway pressure (PAP) therapy titration.
- To inform resource allocation for pediatric polysomnography (PSG).
Main Methods:
- Retrospective review of 274 children undergoing PSG for technology titration.
- Included patients used continuous positive airway pressure (CPAP), bilevel positive airway pressure (BPAP), or invasive positive pressure ventilation (IPPV).
- Primary outcome: predictors of setting changes during IPPV, CPAP, and BPAP titration.
Main Results:
- 623 titration PSGs were analyzed.
- Significant predictors of setting changes included: reason for respiratory technology, type of respiratory technology, and time since ventilation initiation.
- Most patients underwent BPAP titration (n=166).
Conclusions:
- Shorter time from technology initiation predicted setting changes.
- BPAP use was associated with higher likelihood of setting changes compared to CPAP or IPPV.
- Central nervous system or musculoskeletal diagnoses were linked to increased likelihood of setting adjustments.
Study Objectives:
Our aim was to identify clinical predictors associated with changes in settings for pediatric invasive and noninvasive positive airway pressure therapy, which could help inform the allocation of limited polysomnogram (PSG) resources.
Methods:
A retrospective review was conducted in children who underwent one or more PSGs for technology titration. Children were included if they were using continuous positive airway pressure (CPAP) therapy, bilevel positive airway pressure (BPAP) therapy, or invasive positive pressure ventilation (IPPV) the night of the PSG. The primary outcome measure for the study were predictors of change in settings during IPPV, CPAP, and BPAP titration studies.
Results:
During the study period, 274 children using CPAP, BPAP, or IPPV underwent one or more titration PSGs. The mean (standard deviation [SD]) age of the children at the time of the first titration PSG was 10.52 (5.11) y. Fifty percent (n = 136) of the study participants were male. Most patients underwent BPAP titration studies (n = 166), followed by CPAP (n = 83) and then IPPV (n = 25). A total of 623 technology titration PSGs were completed. Reason for respiratory technology, type of respiratory technology, and time between ventilation initiation and the PSG were significant predictors of a change in settings in the multivariable regression model.
Conclusions:
Children were more likely to have a change in their technology settings during a PSG if there was a shorter period of time from the original technology initiation, if they were using BPAP (as compared to CPAP or IPPV) and/or if they had a primary central nervous system or musculoskeletal diagnosis.
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