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Infantile wheeze: rethinking dogma

Fernando Maria de Benedictis1, Andrew Bush2,3

  • 1Salesi Children's Hospital Foundation, Ancona, Italy.

Archives of Disease in Childhood
|October 7, 2016
PubMed

Insights

Wheezing in young children often stems from viral illnesses. Management strategies for preschool wheeze emphasize intermittent bronchodilators for occasional symptoms and cautious controller therapy for recurrent cases, alongside multidisciplinary support.

Area of Science:

  • Pediatric Respiratory Medicine
  • Clinical Immunology

Background:

  • Wheezing is a prevalent symptom in young children, frequently linked to viral infections.
  • It significantly contributes to childhood morbidity and healthcare resource utilization.
  • Differential diagnosis includes conditions mimicking asthma and rarer specific diseases with wheezing components.

Purpose of the Study:

  • To analyze the pathophysiological underpinnings of wheezing in infancy.
  • To critically review the historical evolution of scientific understanding and management of preschool wheeze.

Main Methods:

  • Literature review and critical analysis of scientific progress in pediatric wheezing.
  • Discussion of pathophysiological mechanisms and therapeutic approaches.

Main Results:

  • Management of intermittent wheezing typically involves bronchodilator therapy.
  • Controller therapy for recurrent wheezing requires careful indication and monitoring for efficacy.
  • Multidisciplinary support, environmental factors, and patient education are crucial.

Conclusions:

  • The management of preschool wheeze has evolved, with a focus on individualized and monitored therapeutic strategies.
  • Understanding the pathophysiology is key to optimizing care for wheezing infants and children.
  • A comprehensive approach integrating medical management, environmental control, and education is essential.

Keywords:
infantspreschool childrenwheezing

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