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Acute myeloid leukemia with basophilic differentiation in a 3-year-old Standardbred gelding
Mary Catherine Furness1, Emile Setlakwe1, John Sallaway1
1Department of Clinical Studies (Furness, Setlakwe, Arroyo) and Department of Pathobiology (Wood, Fromstein), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1; Dr. John Sallaway Mobile Equine Services, 1532 Chemong Road, Peterborough, Ontario K9J 6X2 (Sallaway).
Abstract:
A 3-year-old Standardbred gelding with a history of pyrexia, persistent hemorrhage from the oral cavity, and a large, soft swelling at the junction of the caudal aspect of the mandibular rami and proximal neck was evaluated. The horse had neutropenia and anemia, with atypical granulated cells in a blood smear. Additional tests confirmed acute myeloid leukemia with basophilic differentiation, which has been reported in humans, cats, dogs, and cattle but not horses.
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